Which of the following is a symptom specific to gonorrhea in people with vaginas?

Irregular vaginal bleeding is a symptom that can specifically indicate a gonorrhea infection in individuals with vaginas. Gonorrhea often affects the cervix and the reproductive tract, leading to changes in menstrual patterns and potential bleeding outside of regular cycles. This may occur due to inflammation or infection causing disruption in normal hormonal regulation and tissue health.

The other options are not specific to individuals with vaginas; for example, redness around the opening of the penis pertains to symptoms typically seen in those with penises and is not relevant to the female anatomy. Muscle aches and fever are general systemic symptoms that can occur in a variety of infections and conditions, making them nonspecific indicators of infection rather than symptoms unique to gonorrhea in people with vaginas. Thus, irregular vaginal bleeding stands out as a more precise indicator of this particular sexually transmitted infection within the context of female reproductive health.