Which organ systems can be affected by untreated syphilis?

Untreated syphilis can indeed affect various organ systems, with the brain, spine, and eyes being particularly vulnerable. This sexually transmitted infection advances through distinct stages if left untreated, one of which includes a period where it can lead to serious complications in the central nervous system.

The tertiary stage of syphilis is where neurological issues can arise, including conditions such as neurosyphilis, which affects the brain and spinal cord, potentially leading to severe complications like paralysis, sensory deficits, and cognitive impairments. Additionally, syphilis can cause ocular syphilis, affecting the eyes and potentially leading to vision loss.

While other organ systems such as the heart, lungs, kidneys, and liver can be impacted under various circumstances, the central nervous system is notably at risk in untreated cases of syphilis, underscoring the importance of early detection and treatment.